If you 'charge' (defined as entering close combat from a distance) someone then that person, and his friends near him, can take advantage of things that can happen whilst being charged. The most obvious of those is that if you have a firearm and are charged, you get a free attack in the person charging (all other charge-dependant things are Path powers).
However, this would not mean they would ALL have to fight San if she charged, no. Although the one she most recently hit would not be able to fire at you without fleeing combat and giving her a free hit at him.