Padme won't die
Padme is not going to die in Episode 3, here are the reasons I believe this: George Lucas said that the prequels are going to be how everyone got to where they are today, and of course at the end of episode 3, luke and Leiha will be born.
Also, She said she remembers her mother, she died when she was very young. Since Darth Vader did not know he had the twins until later, that could not have possibl been it. Instead, I believe it has to do more with Shmi Skywalker. "Will I ever see you again?" What does your heart tell you? Yes, I guess, then we will see each other again.
"I sense much fear in you, afraid to lose your mothher I think" What's that got to do with anything "EVERYTHING" Do not train him.
Does anyone else agree, disagree, why or why not.
No she isn't. Yoda900 is right about Lucas saying that EpIII would end with the birth of Luke and Leia. IF Padme dies right after, then Luke should have memories of his mother as well, just like Leia. And since he hasn't, it's unlikely. I doubt Lucas will do a "Five years later" thing. Very unSW, every movie takes place with a limited time period. A consecutive time period. No time lapses.
there is no thematic reason why padme has to die in the PT. we already know she dies in ANH when Vader allows tarkin to destroy alderaan. theres no reason to kill her off earlier. (she most likely gives leia over to bail to protect her when she is very young and after that lives in seclusion on alderaan) which brings out an important point that alot of people seem to be missing.
the whole star wars saga is essentially about anakin skywalker aka darth vader. lucas has said over and over again that after viewing the prequel trilogy, we will watch the original trilogy in a new light. there are numerous shots of vader thoughout the OT where we now see him as a menacing evil. after watching the PT, we will see that hes not so thoroughly evil after all. when alderaan is destroyed, we will know vader is thinking that padme is there, and she will be killed, but he doesnt do anything to stop tarkin. he stands there and tacitly supports. that adds a whole new dimension to the films.
to have padme die before that time would also sacrifice a great opportunity to provide continuity between the trilogys, and to bridge the gap b/w episodes III and IV. every other film has overlap, except those two. having padme remain ALIVE at the end of III, and die near the beginning of IV is part of that opportunity.
padme will NOT die in the Prequel trilogy. but she and anakin will become bitter enemies. he will spare her life. in episode iv, he will not save her, showing the progression of his evil from III to IV in the 20 years that separate them.