I disagree. Blade can definitely hold his own. Haven't you seen Blade 2? He took on two HIGHLY trained martial artists with swords at the same time, and was clearly beating them. I think he could definitely handle himself fighting Wolverine. Besides, Blade also has him in pure strength. Agility, I'd say they're evenly matched.
I think this could be a very good fight. But I think Blade would pull through and win.