it will knock him back...but he'll just get up.....compared to an adamantium skin.....no damage can be done......unless spiderman just got chi manipulative powers I'm unaware of...lol.....
anyways....strong guy tried to smash cyber and cyber just kept getting up and knocking him on his butt and was about to kill him too....same prinicipal applies here........cyber got up fine after being smacked full force by a subway train...spidey's not packing that kind of power.......