See, Prep = PIS
This situation isnt "who would win" but rather "can you concieve of a situation where X would win somehow"
so, unless you are really unimaginative, you can probably think of some technology that would be able to take out wolvie and sabertooth, so by default Pun and Fury win, even though in a real two on two they would loose.
So, Kam has already posted a great tactic that "should" work. My suggestion would be a modification of a TMS, (transcranial magnetic stimulation) which allows localized disruptions into brain functioning, into some kind of TMS ray that would disable anyone at location X.
Both of these are very plausable in the comic world given the technology even people like the kingpin have access to, not to mention the formula that works against healing factors.