The End inloved MORE than One Universe,
it involved the entire MULTIVERSE, in fact:
Here we have Zeus summoning the rest of the Pantheons from other Timelines, (UniverseS)
Like Horus:
"Tis also THIER Universe (like 4321) that be imperiled"
And Thanos says,
"meanwhile Doctor Doom was also having HIS Universe (616) badly shaken"
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There's no getting around this,
yall wanted some On Panel Proof that depicted the END taking place in MORE than One Universe,
Well there it is, On Panel.
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Thanos RECREATED the MULTIVERSE ... IMO based on ALL those facts and these:
Eureka!
http://www.marvunapp.com/Appendix3/celestialorderthanos.htm#Heart
"Thanos foiled efforts to stop his plan by Eternity, the Living Tribunal etc ...
but he also Obliterated the Multiverse in the process"
"Thanos did so, using the Heart's power to Re-Create the Multiverse
bereft of the flaw that would have destroyed it"
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Marvel 2006 Handbooks:
Thanos gained THOTI ... LT joined champions across Reality ..
Thanos destroyed All that existed"
(excerpt from the Official Marvel Handbook 2006 LT - Bio)
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"Thanos claimed THOTI ... Eternity opposed ... Thanos destroyed All of Reality"
(excerpt from the Official Marvel Handbook 2006 Eterntiy - Bio)
Also, notice the reference made to Genis and Entropy destroying the same Eternity.
Genis and Entropy destroyed the Spirit/Consciousness of the Totality of Eternity (the Multiverse)