1. If you are an superhero, you will automatically get super-speed thinking, even if you don't have any powers at all:
"Oh no, Hulk's fist...about to hit me! If I only had more time to move...this is going to hurt so much."
Or:
"Oh my God...Ned is going to die...Green Goblin will reach him in seconds...if I only had more time to save him...now he will die..."
Uh, I don't know...how about actually moving, instead of thinking about it...
Or, "Only millisecond to react...must reverse the polarity of my enemy using the Laws of Newton..."
And somehow, if they have only millisecond to react...they can devise plans in that time.
2. NEVER try to know the secret identity of superhero. Chances are, if you know it, you will die in painful and tragic way on the ame day.
3. NEVER be close relative to an superhero or someone with superpowers...you will either die in the first 10 issues, be tortured for a month, or go in coma. If you are close relative to someone with superpowers, your tragic death may cause him to be superhero/villain, depending on the situation.
4. Highly trained police officers can fire an rainstorm of bullets towards an superhero and never hit him. Only higly trained assasins and supervillains have an change to hit an hero.
5. Don't fight Wolverine unless you are above herald level. He will win.