Spidey and Pals versus Mutants
Two teams:
TEAM SPIDEY:
Spider Man (from SM3)
Both Goblins (Harry and Norman, no flesh eating bullshit bombs, but they have their gliders and the rest of their weapons.)
Doc Ock
Sandman
Venom
TEAM X MEN:
Wolverine
Storm
Colossus
Pyro
Iceman
Cyclops
All out battle to the death on Alcatraz island, at night.
Who wins? No prep, and neither side has knowledge of the others abilities.