Hell
Let's discuss the Empire State Building as an example *shrugs*
https://www.google.com/#q=mass+of+empire+state+building
Approximately 331,000,000 kg? Lifting that a meter gives you about 0.775 tons of energy to lift it.
Or just shy of a conventional tomahawk cruise missile in yield (some 450 kg/0.45 tons according to the admittedly citationless wikipedia article *shrugs*)
What do you all think are the odds of that kind of ordinance conventionally damaging the ESB significantly?
Not talking "take out the supports and watch it fall" I mean "wreck the material through the bomb's own power"