Wolverine would make this a very difficult fight for the FF to win because Sue isn't going to be able to just maintain forcefields indefinitely and Wolvy can slice Mr.Fantastic.
The nova blast is something that Johnny can't surprise the foursome with because Spider-man's danger sense will go nuts as soon as Johnny makes up his mind on this course of action. Spidey will know that the only thing that could make his Spider-sense blare, warning danger from every direction is the nova attack that only the torch is capable of. With a quick shout to his teammates and a webbing shield over himself and Storm and they WOULD survive the blast. ( Collosus should be alright and would probably protect Wolverine from the blast enough to keep him alive. The FF would have to be protected from the blast by Sue as well and that may be a problem as they will all be very busy.)
The Thing is outmatched by the combination of Wolverine and Colossus as he cannot ignore either one and though he may knock Wolverine out he'll regain consciousness before his team is defeated. Sue is the only one on the FF's team that can put Collosus out of commision and like I said before she will be quite busy protecting herself. She can't hide because Wolverine WILL smell her.
Johnny Storm's weakness should be exploited immediately as Storm causes the battle field to be caught in a torrential rainstorm.
In an all out fight, the Fantastic Four would be outmatched battling three very powerful mutants and an unrelenting Spider-man.