The imediate future for gaming overall imo will be the two blizzard games Diablo 3 and SC 2, they wll rock the world even if they seem simple.
Personally to me, both of them, then add DOW 2
I think someone needs to grab the idea of Spore, then make it bigger in gameplay, already its massive in its ideas and uniqueness, and ofc no gaming environment (literally hundreds of thousands of solarsystems, perhaps millions of planets) is as big, but it needs more imo to do in this large space.