Originally posted by quanchi112
Id say something like Mephisto trying to take Galactus' soul. He wouldnt attempt it because he would realize it wouldnt work imo and not waste the effort.
Different set of circumstances though because it's actually been confirmed on panel that the Soul Gem's jurisdiction both encompasses and extends beyond Mephisto's and Galactus is beyond the jurisdiction of the Soul Gem. Thus the claim isn't baseless because it has actual on panel confirmation. What's more, Galactus and other abstracts are regarded as omnipotent(or nearly so) so it's not really speculation to acknowledge the likelihood of their resistance because technically they're supposed to be able to do pretty much ANYTHING up to a certain point. You can speculate on the abilities of abstract level characters till you're blue in the face if you want and I seriously doubt that I or anyone else will have a problem with(hence statements like "Galactus turns him into a cheeseburger" despite his never having done that).
I'm talking about characters with actual limits to their powers.