xkalybr
The Sword of Power!
I just want to keep it real. Cap is a normal human facing a super human in Spidey. That in itself should determine a victor, but let's get specific.
With all of Caps fighting skills, limited human speed and limited human strength, if he got lucky enough to hit Spidey, it should not hurt Spidey. Remember that Spidey has been hit by the likes of the Hulk and the Submariner and stayed conscious.
Spidey, as we all know, has super human reflexes. Fast, fast, fast. Mix in his spider sense which warns him of all danger coming his way, to include kicks, punches, bullets, knives, lasers, and Cap's shield. Spider sense and reflexes means Peter won't even get touched if he doesn't want to get touched. Cap would not lay a glove on him. For every lucky one punch Cap lays on Spidey, Spidey in return should land 5 punches.
I haven't even mentioned Spidey's super human strength. Imagine Cap getting bombarded with all those super human strong punches?
The numbers simply don't favor Cap because he is simply overmatched. Just like Batman, Daredevil and Nightwing would be overmatched. If Wolverine didn't turn into this unkillable character who looks like he could live forever, I think Spidey could take him.
If Peter was less of a clown, though I find him to be funny, and was more focused, there would not be too many villians or hereos he fought that could beat him. Spidey is a damn tough character who is underratted vs some people he fights.